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Washington
(H24N).
Women far outnumber men when it comes to giving up their kidneys
to loved ones with kidney disease, and researchers at the University
of Toronto wanted to know why.
So
they set about examining 144 living-donor kidney transplants to
see what prompted women to donate more often than men. Their findings
are published in the September issue of the American Journal
of Kidney Diseases.
"Numerous
studies document that women constitute the majority of living kidney
donors, but the reasons behind the disparity in donation rates between
men and women remain obscure," write the study’s authors. "We
studied this issue by gathering data on family members of living
donor allograft recipients at a single, large center over a five-year
period."
The
researchers looked not only at the gender of the donors, they also
looked at the characteristics of all of the potential donors within
their family circles. They found that 28.3 percent of all medically
and immunologically acceptable female family members went on to
donate, whereas only 20.3 percent of all compatible males went on
to donate.
The
researchers found no gender-related differences in donation rates
among first-degree relatives, but among spouses, they found that
36 percent of the wives who were acceptable donors went on to donate,
compared to only 6 percent of the men who were able to donate their
organs.
"The
gender disparity among living kidney donors observed in our population
can be largely attributed to an overwhelming predominance of wives
among spousal donors," the authors report.
Although
the study doesn’t examine the reasons why wives donate their organs
more readily than their husbands, the authors offer some possible
explanations: that some women may view donation as "an extension
of their obligation to their family," and there may be a reluctance
on the part of families to risk "the loss of income of male
family members for the purpose of donation."
They
conclude that in order to expand the pool of living kidney donors,
the medical community needs to pay more attention to "gender-based
attitudinal differences toward donation."
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