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Washington.
Celera Genomics announced June 26 that it has completed the first
working draft of the human genome, having sequenced 99 percent of
the genome using its once controversial "shotgun" approach.
During
a joint press conference, the Human Genome Project public consortium
said that it has assembled sequences covering 85 percent of the
genome and has cloned 97 percent of the genome. "Almost half
of the genome is in finished or near-finished form," said Francis
Collins, MD, Ph.D., director of the National Institutes of Health’s
National Human Genome Research Institute.
The
gaps in Celera’s 99 percent sequenced genome "don’t add up
to much," Celera’s president and chief scientific officer J.
Craig Venter, Ph.D., said at the conference. "We have 3.12
billion letters of the genetic code that have been assembled,"
he added.
"We
will see coming out of this the blossoming of the field of pharmacogenomics,"
Collins said. The data will generate "thousands of new drug
targets, which will turn out to be the source of blockbuster treatments
in the future," he added.
In
a White House press conference last week, President Clinton stressed
the importance of "public-private cooperation" in maximizing
the potential of genetic research.
"Public
and private research teams are committed to publishing their genomic
data simultaneously later this year, for the benefit of researchers
in every corner of the globe," Clinton said. "And after
publication, both sets of teams will join together for an historic
sequence analysis conference. Together, they will examine what scientific
insights have been gleaned from both efforts, and how we can most
judiciously proceed toward the next majestic horizons."
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